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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4486d01dcd912346f405147e202b174c7638618da65ae310bfed824130fb75ed' 
  AND token = 'TuBLq2FGWeAqyfdn1svs5ycLpYF7cIBcsmpl7ZsclwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}