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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18523ee8f50d58efaf4a46abaa042427f43f2687ea8c92248848053fa7cf7a8a' 
  AND token = '+dNaaMoCVH0bNNmbg0aiOi7u3rpLWT4NhpqhyoI+LGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}