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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9c16e9cf2c0d94b03fa72f05da393ff56421a1790669332f34ee0385ab2a174' 
  AND token = '9Ac2Z7/BaQVQOXgBtc49nLyihReaK+WOOPg3E64ni/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}