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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8dd21baa5d074d4a805d7e6803e5881c6da7eb86b002edbab1531c79ec83639' 
  AND token = 'V+VhM6gTRZSvNHMDIY9cNl5dzhtIlvdxaDbSY0pbtuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}