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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d54a8e04784ee647561b20060aa39c0e94ea0c99c05139674d198d14049c207' 
  AND token = 'v6Fa4ddhXUVs5WGsbMpuvPC2LNiPdyRWAm5nxVjpzpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}