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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d3b69d4f7378cbd22457daba00d03b2f7dd46bd7da18abc42f6019596040e65' 
  AND token = 'BO0M/z7OUvh/F1WfwBohQfbExRGZqYhqqSz81c/7b5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}