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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e7379fa4e40aea5b468ae38ca0f553dd135de345de15031c4013921be1cb6e3' 
  AND token = 'tnoJlXag/rNiMMgTDgJI2gi3x6jSSKQVH/wR1zpyv/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}