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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5f6df278b9f072bc6b944291e29ab6fae510b37e72c96d69641df71adf6177c' 
  AND token = 'ZNLrV41Bz2MDxUAcDsGNvrz+eTc6q+v4z1F+KBgQksQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}