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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '165bfdbe9b51e01375244b9677406c8196ccd949b35ca47b080b8dbd26255fe8' 
  AND token = 'rkgBZCMiB/Hy6ABGVE0eDVaOceRO89ROGgPGJaUec+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}