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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c9d95b9de52d859eb685ffff0bde4406023d6da54b10dc00fc5fb621edda2ed' 
  AND token = 'eF5tWCb/G/P+jekxFFSRIPKpScrE0Tz0rfDGB+TpB7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}