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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9710448d53d5fcf6f8d3aba77f6f31d6d6be21cc2cc78fe2939d1032994970d7' 
  AND token = 'GDsfrQ69PTPC4iMzBF39oOlnYEHZuYV3i70hG+7djXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}