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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9be8f22db405b37a091fe931a129e74d49caa9ab2d91eddfee4bb2fd08612488' 
  AND token = 'oryc6Op7RmonONWG2sijt2KProS3JTKTTUCYL22g1w4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}