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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a138a0116b3e615e0e6b8a8952ceb2c403f3da84b1469e83b2b0e272d52da7f1' 
  AND token = '0+NR/55Bhto6CFXb/cfHiq2TGBbacQj9LnH2kAXZ1K0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}