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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '493f6b9b0f6d80b03c430e6fa9d348b9984cfd760b6ecc555f548c348a269fb6' 
  AND token = 'vMpqm0Ae6VZz/IqgmaKXx3V1V2L44zD6f6l3gXuuNXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}