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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd7495964bc40e28999b2c4c9543417dc830a8981491c308da209823f5a7f1d8' 
  AND token = '5+Z4OGQTT6CzPRTdi0TS+MjFt6S8FW4YWEzNNIu8E7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}