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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0362d8953de5d2273e0147450b6f20d739da2a82728c1e813066468157b74bf' 
  AND token = 'KWq3HittnQWxbtODnXeSaPuPGaVQdNyUHIZ1OJz+oGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}