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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '418326874be3d6b403833a46a6f8bf9f258ab983c1532882bf6e64edca30e1af' 
  AND token = 'joOiy/9rafoEum3+Ibnb5Qr0fs4cpUhnYVNOlgQYWZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}