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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d4a51bdede56eab7bbf443078fa7815b7367e6d668477d130713f41e6440179' 
  AND token = 'F+E+B+L1rARQ4es4hdpQzw3AIyyueff9h0p9KL1VhNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}