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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fe8c60b5412fc4aacbc042afd8acfee97f33cb80d933538e906b1121c15014d' 
  AND token = '1d0ybHuFgVwzsJF+xboPosTSnGwTtyb465HbxtH9guw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}