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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7943b9979835e8ccae21fd3442330f4930aa009bd0d89a7d5a736db69b76ed67' 
  AND token = 'UuqFI+lMBkcvxnN1sFxU288L1c49AG8HJdLxEWzZG8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}