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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd12cb2b305cd8a160881af274a8c14edc3cd9d1e477e20b89500429cda7e758d' 
  AND token = '8mJ593YnTHvOSXCuGDcWkVZoPHf4bqi+NDUTh9sCb6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}