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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19f6e03301f575e1f816adb8b0b0b72a2378a1b3b40b1c4d2aaab29f95476321' 
  AND token = 'teePecIdb+f2/RA4OcFxEs8lTqnGYQq9RUXXc796kb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}