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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '533b4fdb5c9e30d5747cd3b88a4e96f2d2020f3e41100dc65aa20b18b963ba81' 
  AND token = 'kix80hkJfNYe0CrXcV9b22U/w4QDolAYPoqzPPCA7fw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}