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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df8032457c2fd005cd0442ca4e1a93f3dbdcfb12f9573a5765098204b229573d' 
  AND token = 'F+x4nh0An6FfrJ/VcbKOjcVMqtLjTGK71vL7D/Zadi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}