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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2e45aa6df281d38c44cad75ed1e3c455ee7eb03baa758c27862bdfc1fd28535' 
  AND token = '7HlnU02VCRTkhg8UhsUIww/g3u40SRVxonR5bGDH48o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}