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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f28634795b8a9c68c006b64158a74d270d5bd4bc9a32787d2d74f456c38bb56d' 
  AND token = 'AdSldZW49Le6jNqJyYgfHtG7UCWDO1XwB9lLPMOMU44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}