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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '819178f2d897f7dec5061ed5318e86bf8946c576dc7491dc58d67360c27e9da4' 
  AND token = '9RNIzzcP5+bkPD6uYNdsI0gdGioDZae3ESO9sDGi+0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}