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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64133c437d7f44c367902d3b0289f69d9d411b636504a0cf2666866ca19de479' 
  AND token = 'KrcTV0JBTHbMt29PBEw4z009iFvqITqhXtGKSZQ7bHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}