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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f53e59a4029a0731cb71ba22b7f1f8e5e119cec6c844ee0bd0ec927dbadbd0d3' 
  AND token = 'QHpMFviZYAvYBh2YmI/PMN3Id6me8OjSfgv31mukpWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}