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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f2bf09daa91048f2f994d7b93c0e2366ec587cb6d4e6bcac35a99bb02dde072' 
  AND token = 'AwzYdKN1/dTFJMLGy6CKw8fFhpYMuy2vGKQbx1DsF0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}