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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c50b6121ffa912b0561e1f2a19b96ef7cba7dd9ad7d431e6d6a60465d7963e9' 
  AND token = 'mB3SgiFqZ7GlCcYRpqAl3eL0S0b9qLJUniNpDmmojmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}