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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e527eebec906f5e69071caeb768c0a87f58efe13900ff164825037dc2c063e1c' 
  AND token = 'lKGlEOJd5JW4Mn6Xu0/TssH9ZOcpBcnlIeQtl+nYRrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}