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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67e8d9e1c85b09ba8a8c651c306e816466c9aebd6eedc53b842c0778423dd2af' 
  AND token = 'vPWbz/zswaECyNNsTbnObDR8t0u0GCK129vTHRUEM7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}