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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38f7f554465096a435da7e9d67eb95127413d9b09d9e061ffce106a985595487' 
  AND token = '1egMxfbB1E88rftWSmy23XLYG1GNQHbpY4U9sKET+sU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}