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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7153b34094de48aec678435a1f03b9daa95fb045b01656eee86d3a94b60f709f' 
  AND token = '+jBWycsoh2P/OR9MGczt+eanwN2PFX7KgDgiD+k22eY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}