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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '854014c4f3b6837e40d167cdb8253c42de4b01d79e0d2d04787818d1d9be854a' 
  AND token = 'VaiTyQfu1djVxprS7s9bXiNIwrHNYaZgbsyTuCidGB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}