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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b7171aa65d8b6ba8f00f5214016f3becc104ec85a7c3289d971dc7f85ac23cb' 
  AND token = 'YXTeBgFzlbu2nJt3b5jBk66irTA8c0VQXtVscnZ5xdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}