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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f975387566f6dc27cf14eec0f6ca1f13e7fc86ac81204320d9029f128e5dc2' 
  AND token = 'tl1ZttCm3WGMlGkDTFmw9PYQZKzeMvxGNkc0WZWq+gU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}