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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd6c7311d1a09a908abd0b94550d3d16e89078942af17b0663451d41724c9fa9' 
  AND token = 'FunW58UaNTk0Kk0blNxSVhLLZM+6Vwvn/ficDUYw6hA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}