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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fdb1e5389bcf8b04de0b15c6a165c3336ffec1180f722f219eb13828d025d1c' 
  AND token = 'cvrtyCRf7alXEj61/n6ArYGQxqhLLw6qa9xXg1BD5iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}