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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a4a0571725329a43df7ac34360812bc7af1cbcd7a6600b9808b979f27023ec5' 
  AND token = 'IDtFOiA5F55PTr6Tso8O3pmFPcQZxECXp6M8OfJ2WjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}