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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '749e0e8bec755f9a7367e072a3a2af6af9374a26c46edc421ee696d83339c49e' 
  AND token = 'aOTK3+wDjDIMjhiy9Qo7B8cpgNVOFmihbkmWGT3zsnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}