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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17fad69a5a018d9827cfd116894169525f93eb217068828b1d644d8145f469e1' 
  AND token = 'ls2ItiIGRBsxwXwle2fihzxhNNij73yjkagDoWRUy5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}