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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94b29c331558875c89e86841f9452551aed49997814c76410ac72856862c265f' 
  AND token = 'R4ReRbQ/BGmfbgT4AK6A6hiHSXRGlGrEZ3ZnlutvqSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}