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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81e28b8e960991796aec9d8b81f8f49ede7abf626dd9ad83cc4c2929650bba59' 
  AND token = 'kft8Gy4h/z6KA6QVI5TWgf3PJb1wE2IykyRffNop9Jc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}