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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3b9fba4b01c027e8bac3733eb9bf1a529c83b386972a5d0a8dc80da22c9cee7' 
  AND token = 'tgBN7HzYg/zeivmQTmob+289H2hrh5Ybky+1MAJzQ2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}