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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6388ace3e569644d3baddf63490fee31bd047d56c6a5cec7de430d0a438bc54' 
  AND token = 'Bj1bJvQwJbGw4vSFVTKbEft0EMbXrQvJCLVGv2Af/Sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}