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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '212a6ecae7a108eb3e299bcb1d07f046bf0e5fcca7101f9ae2280f639e2700d8' 
  AND token = 'RplUorDtbC8mg6sHI+pQenV1nQEMcMau1SVkyUkd4b8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}