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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '525acd306ef593991b511a2e7b8ddd303b61bf37208f194cbafc68a9c21222df' 
  AND token = '2gxAlM2jO5QEqScOEdizFVlAWsQSeR/TKtF1ElCSGLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}