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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45f33fd6f88256b2e2e77b0efd94e5f33b1c2e13c78c31da41690c54c80f5988' 
  AND token = 'AIYMnEtaqzUAsdV2ITyVfnJnGJl1gJVl1PJ/5yq/NLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}